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CBSThe ongoing 12th season of “The Big Bang Theory” is its last. So you can bet that in their final go-around, the show will try to recruit just about every guest star in the galaxy. But TBBT has already had a nerd’s fantasy of astronauts, physicists and Spock. Ahead of its series finale, TheWrap looks at some of the show’s most memorable cameos. Excelsior!

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CBS“Hot in here? Must be Summer.” How many times has “Firefly” star Summer Glau heard that one? In this Season 2 episode, she has to endure the advances of both Howard and Raj as they try to pick her up while traveling on a train.