Aaron Eckhart will play Adam Frankenstein in the Lakeshore Entertainment, Hopscotch Features and Lionsgate production of I, Frankenstein, the companies announced on Friday.
The film is a modern-day retelling of the Mary Shelly classic. In it, Frankenstein's creature has survived into the present day because of a genetic quirk. Making his way to the city, he finds himself embroiled in a centuries old war between two immortal clans.
No word yet on if Adam, the part Eckhart plays, is the creature or his creator.
Shooting will begin in Australia in January.
The film was written and will be directed by Stuart Beattie (writer of "Pirates of the Caribbean" and "Collateral"), and is based on a graphic novel by Kevin Grevioux, co-creator of the "Underworld" franchise.